The nasal cavity represents a potential site of transmission and replication of the SARS-CoV-2 virus in the initial stage of COVID-19. SARS-CoV-2 is an enveloped virus of the Coronaviridae family. Its outer envelope (pericapsid) consists of a phospholipid bilayer membrane.
Phospholipid bilayer membrane
ViruBLOC Nasal Microgel is composed of 3 main ingredients: glycerol, hydroxypropyl methylcellulose, and Nicomenthyl® (menthyl nicotinate, a vitamin B3 derivative), acting in synergy to create an efficient triple action of chemical-physical and mechanical nature:
- TRAP: glycerol and hydroxypropyl methylcellulose create a transient and osmotically-active mucoadhesive barrier, which traps the viruses.
- DEACTIVATE: the lipid/amphiphilic structure (i.e., having both hydrophobic and hydrophilic character) of Nicomenthyl® interferes with the viruses’ pericapsids (also of lipid and amphiphilic nature), disrupting their conformation and preventing them from penetrating and infecting the cells.
- PROTECT: the barrier of ViruBLOC Nasal Microgel protects the nasal cavity, stimulating mucous secretion (one of its most important natural defenses) and helping to remove the deactivated virus (towards the stomac or blowing the nose).
WARNINGS
Carefully read the information provided by the manufacturer before use.
ViruBLOC Nasal Microgel does not replace face masks and all the other protective measures against SaRS-CoV-2 recommended by healthcare authorities.
You may notice increased nasal secretion (runny nose), nose discomfort, or temporary tingling during use. These signs are normal and indicate that the product is working correctly. Stop using the product if the sensation persists.
Stop using the product and seek medical advice in the event of adverse reactions.
Seek medical advice in the event of high fever or if the symptoms are more severe than those of a common cold.
Do not use this product before nose or throat surgical wounds have healed without seeking medical advice.
Seek medical advice before using this product with other nasal products.
Do not exceed the recommended dose. Do not use this product continuously for more than 30 days in a row.
Do not spray into eyes or areas other than the nasal cavity. In case of accidental eye contact, rinse thoroughly with running water.
Do not use if its packaging is open or damaged.
Do not use after its expiry date. The expiry date refers to the product stored correctly in undamaged packaging.
Application on children should be done or supervised by an adult.
Keep out of the reach and sight of children.
Rinse the applicator under running water and dry it before putting the cap back on.
Do not share this medical device with anyone else to reduce the risk of virus spread and cross-contamination.
Note: The above corresponds to the full text of the instructions for use of the medical device ViruBLOC Nasal Microgel Spray Ref. 2101134R6